SCHEMBL762808

SCHEMBL762808

COC(=O)c1cc(CCl)cc(C(=O)OC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
KDM4E B2RXH2 3/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
NFKB1 P19838 1/20 0.50
XDH P47989 1/20 0.50
GFER P55789 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
FUT7 Q11130 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 4/20 0.49
LOXL2 Q9Y4K0 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13524799 0.89 ALDH1A1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL7718881 0.89 SLC7A5 (0.59) CA12CA1CA2CA7CA9
SCHEMBL7013307 0.89 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL16010428 0.87 NOTUM (0.53) CA12CA1CA2CA7CA9
SCHEMBL31371278 0.87 CA1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL16729319 0.87 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL31385453 0.87 CA1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL762861 0.85 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL12944867 0.84 KDM4E (0.42) CA12CA1CA2CA7CA9
SCHEMBL16727002 0.83 NOTUM (0.60) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700955-B Antibacterial PET film material and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-05-10 CN claimed
CN-117700955-A Antibacterial PET film material and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-03-15 CN claimed
CN-117700955-B Antibacterial PET film material and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-05-10 CN disclosed
CN-117700955-A Antibacterial PET film material and preparation method thereof 佛山市奥川顺新材料实业有限公司 2024-03-15 CN disclosed
US-20220062323-A1 BIVALENT TARGETED CONJUGATES ARBUTUS BIOPHARMA CORPORATION (CA) 2022-03-03 US disclosed
US-20220062323-A1 BIVALENT TARGETED CONJUGATES ARBUTUS BIOPHARMA CORPORATION (CA) 2022-03-03 US disclosed
US-20220031847-A1 THERAPEUTIC METHODS GENEVANT SCIENCES GMBH (CH) 2022-02-03 US disclosed
US-20220031847-A1 THERAPEUTIC METHODS GENEVANT SCIENCES GMBH (CH) 2022-02-03 US disclosed
EP-3873530-A1 THERAPEUTIC METHODS Genevant Sciences GmbH (CH) 2021-09-08 EP disclosed
EP-3873486-A1 BIVALENT TARGETED CONJUGATES Arbutus Biopharma Corporation (CA) 2021-09-08 EP disclosed
CN-113365662-A Method of treatment 盖纳万科学有限公司 2021-09-07 CN disclosed
US-7585364-B2 Quinacridone derivatives for pigment dispersions AGFA GRAPHICS NV (BE) 2009-09-08 US disclosed
US-7585364-B2 Quinacridone derivatives for pigment dispersions AGFA GRAPHICS NV (BE) 2009-09-08 US disclosed
CN-101522828-A Non-aqueous pigmented inkjet inks AGFA GRAPHICS NV (BE) 2009-09-02 CN disclosed
US-20080314285-A1 Quinacridone Derivatives for Pigment Dispersions AGFA GRAPHICS NV (BE) 2008-12-25 US disclosed
US-20080314285-A1 Quinacridone Derivatives for Pigment Dispersions AGFA GRAPHICS NV (BE) 2008-12-25 US disclosed
US-20080295734-A1 a mixture of organic pigments, and a a dispersion synergist containing acid groups or salts AGFA GRAPHICS NV (BE) 2008-12-04 US disclosed
US-20080295734-A1 a mixture of organic pigments, and a a dispersion synergist containing acid groups or salts AGFA GRAPHICS NV (BE) 2008-12-04 US disclosed
US-20080269381-A1 a mixture of diketopyrrolopyrrole dyes, polymeric dispersants and a quinacridone derivative containing acid groups or salts AGFA GRAPHICS NV (BE) 2008-10-30 US disclosed
US-20080269381-A1 a mixture of diketopyrrolopyrrole dyes, polymeric dispersants and a quinacridone derivative containing acid groups or salts AGFA GRAPHICS NV (BE) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080314285-A1 Quinacridone Derivatives for Pigment Dispersions RB1, NDUFS2, NDUFS6 CA12 4151/4885CA1 4836/4885CA2 4224/4885
US-20220062323-A1 BIVALENT TARGETED CONJUGATES ERBB2, PCNA, MRE11 CA12 542/4885CA1 1594/4885CA2 1922/4885
US-20220031847-A1 THERAPEUTIC METHODS NUP205, HNRNPH3, FUS CA12 786/4885CA1 2020/4885CA2 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.