SCHEMBL29827128

SCHEMBL29827128

NC(=O)NCCC[C@H](NC1CCC1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX2 P34913 4/20 0.42
▸ C3AR1 Q16581 1/20 0.41
▸ SHMT1 P34896 1/20 0.37
▸ CPB2 Q96IY4 2/20 0.36
▸ EPHX1 P07099 2/20 0.35
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ ARG1 P05089 1/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30645458 0.84 SMN1; SMN2 (0.44) SMN1; SMN2EPHX2C3AR1SHMT1CPB2
SCHEMBL27632265 0.84 SMN1; SMN2 (0.45) SMN1; SMN2EPHX2CPB2EPHX1
SCHEMBL31416512 0.82 SMN1; SMN2 (0.42) SMN1; SMN2EPHX2C3AR1SHMT1CPB2
SCHEMBL1345737 0.82 EPHX2 (0.37) SMN1; SMN2EPHX2C3AR1CPB2MEN1
SCHEMBL7628167 0.82 EPHX2 (0.37) SMN1; SMN2EPHX2C3AR1CPB2MEN1
SCHEMBL32665433 0.78 C3AR1 (0.37) SMN1; SMN2EPHX2C3AR1SHMT1CPB2
SCHEMBL21167241 0.78 KMT2A (0.41) SMN1; SMN2EPHX2KMT2ALMNA
SCHEMBL9181564 0.76 CPB2 (0.55) CPB2
SCHEMBL9181567 0.76 CPB2 (0.55) CPB2
SCHEMBL6562366 0.75 GRIN1 (0.47) SMN1; SMN2EPHX2C3AR1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 — — WO claimed
WO-2025120085-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 — — WO claimed
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 — — US claimed
US-20250177546-A1 ROR1-TARGETED BINDING MOLECULE AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2025-06-05 — — US claimed
WO-2025109097-A2 NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-05-30 — — WO claimed
US-20250171419-A1 NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-05-29 — — US claimed
WO-2025031307-A1 MULTIDRUG LINKER AND ANTIBODY-DRUG CONJUGATE 上海华藕生物医药有限公司 2025-02-13 — — WO claimed
CN-119371541-A ROR 1-targeted binding molecule and application thereof 杭州中美华东制药有限公司 2025-01-28 — — CN claimed
EP-4491632-A1 ROR1-TARGETED BINDING MOLECULE AND USE THEREOF Sanyou Biopharmaceuticals Co., Ltd. (CN) 2025-01-15 — — EP claimed
US-20240384269-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSIOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2024-11-21 — — US claimed
CN-118574845-A ROR 1-targeted antibody or antigen binding fragment thereof and application thereof 杭州中美华东制药有限公司 2024-08-30 — — CN claimed
EP-4404974-A1 ANTIBODY-DRUG CONJUGATES Spirea Limited (GB) 2024-07-31 — — EP claimed
EP-4323517-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2024-02-21 — — EP claimed
WO-2023169328-A1 ROR1-TARGETED BINDING MOLECULE AND USE THEREOF 三优生物医药(上海)有限公司 2023-09-14 — — WO claimed
WO-2023047090-A1 ANTIBODY-DRUG CONJUGATES SPIREA LIMITED (GB) 2023-03-30 — — WO claimed
WO-2022219409-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2022-10-20 — — WO claimed
WO-2026100671-A1 ANTI-GPRC5A ANTIBODY AND USES THEREOF リベロセラ株式会社 2026-05-15 — — WO disclosed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 — — WO disclosed
WO-2023047090-A1 ANTIBODY-DRUG CONJUGATES SPIREA LIMITED (GB) 2023-03-30 — — WO disclosed
WO-2022164942-A1 PNMA2-BASED CAPSIDS AND USES THEREOF VNV NEWCO INC. (US) 2022-08-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES BCR, TBCD, TBC1D5 SMN1; SMN2 3568/4885EPHX2 2482/4885C3AR1 2266/4885
US-20250177546-A1 ROR1-TARGETED BINDING MOLECULE AND USE THEREOF RORB, RORA, RORC SMN1; SMN2 3377/4885EPHX2 1499/4885C3AR1 2009/4885
US-20250171419-A1 NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF NAMPT, NAPRT, NNMT SMN1; SMN2 2735/4885EPHX2 2212/4885C3AR1 2379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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