SCHEMBL762846

SCHEMBL762846

C=C(C(=O)O)c1ccc(C#Cc2ccc(-c3ccc(CCC)cc3F)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.50
KDM1A O60341 4/20 0.40
FFAR1 O14842 2/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MPL P40238 2/20 0.38
ACACB O00763 2/20 0.37
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DGAT1 O75907 1/20 0.35
SOAT1 P35610 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL762946 0.82 ACACB (0.50) FFAR1FFAR4ACACB
SCHEMBL19845067 0.81 ESR1 (0.42) RARBFFAR1FFAR4
SCHEMBL15797758 0.81 RARB (0.67) RARBMPLRARARARGNPC1
SCHEMBL8988787 0.81 RARB (0.41) RARBKDM1AFFAR1FFAR4ACACB
SCHEMBL14228880 0.79 GRM5 (0.41) RARBKDM1AFFAR1FFAR4ACACB
SCHEMBL14525801 0.79 RARB (0.40) RARBKDM1AFFAR1FFAR4ACACB
SCHEMBL29306100 0.79 TSHR (0.46) RARBKDM1A
SCHEMBL13211613 0.79 RARB (0.51) RARBMPLACACBRARARARG
SCHEMBL74657 0.79 THRB (0.57) RARBKDM1AFFAR1FFAR4ACACB
SCHEMBL10923045 0.79 RARB (0.56) RARBMPLNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-8009266-B2 Process for producing liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2011-08-30 US disclosed
US-7892449-B2 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2011-02-22 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 US disclosed
US-20100060844-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-11 US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 US disclosed
EP-2093610-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY ELEMENT Dai Nippon Printing Co., Ltd. (JP) 2009-08-26 EP disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 RARB 3123/4885KDM1A 2102/4885FFAR1 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.