SCHEMBL7628593

SCHEMBL7628593

CCN(O)c1ccc2cc[nH]c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.49
TYR P14679 1/20 0.47
ENPP2 Q13822 2/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
AHR P35869 3/20 0.43
CMA1 P23946 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
GLI1 P08151 1/20 0.40
GLI2 P10070 1/20 0.40
CYP2A6 P11509 1/20 0.40
NLRP3 Q96P20 1/20 0.39
OPRM1 P35372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616880 0.82 TERT (0.52) MAOATYRENPP2MEN1POLB
SCHEMBL31084784 0.76 AHR (0.50) MAOATYRENPP2MEN1POLB
SCHEMBL827584 0.76 AHR (0.50) MAOATYRENPP2MEN1POLB
SCHEMBL21318456 0.74 NLRP3 (0.56) MAOATYRENPP2MEN1POLB
SCHEMBL8433227 0.73 TYR (0.44) MAOATYRENPP2MEN1POLB
SCHEMBL26312941 0.73 MEN1 (0.47) MAOATYRENPP2MEN1POLB
SCHEMBL27534535 0.72 ENPP2 (0.50) MAOATYRENPP2MEN1POLB
SCHEMBL3425918 0.72 GLI1 (0.55) MAOAENPP2MEN1KMT2AKDM4E
SCHEMBL14487695 0.71 ENPP2 (0.53) MAOATYRENPP2MEN1POLB
SCHEMBL15324284 0.69 GLI1 (0.50) MAOATYRENPP2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544874-A1 METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS L'OREAL (FR) 1993-06-09 EP claimed
WO-1993000068-A1 METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS L'OREAL (FR) 1993-01-07 WO claimed
WO-2002102333-A1 COATED ORGANIC PIGMENT AND COSMETIC COMPOSITION CONTAINING SAID PIGMENT L'OREAL (FR) 2002-12-27 WO disclosed
EP-0636360-B1 Cosmetic composition containing an association of a superoxide dismutase and a melanin pigment OREAL (FR) 1998-06-17 EP disclosed
EP-0659070-B1 COSMETIC COMPOSITION CONTAINING SOLID PARTICLES COATED WITH AN AMPHOTERIC POLYMER OREAL (FR) 1997-05-07 EP disclosed
EP-0659069-B1 COSMETIC COMPOSITION CONTAINING SOLID ORGANIC PARTICLES COATED WITH A CATIONIC POLYMER OREAL (FR) 1996-11-20 EP disclosed
EP-0659070-A1 COSMETIC COMPOSITION CONTAINING SOLID PARTICLES COATED WITH AN AMPHOTERIC POLYMER. OREAL (FR) 1995-06-28 EP disclosed
EP-0659069-A1 COSMETIC COMPOSITION CONTAINING SOLID ORGANIC ARTICLES COATED WITH A CATIONIC POLYMER. OREAL (FR) 1995-06-28 EP disclosed
EP-0636360-A1 Cosmetic composition containing an association of a superoxide dismutase and a melanin pigment L'OREAL (FR) 1995-02-01 EP disclosed
EP-0425345-B1 Keratinic fibres dyeing process with amino-indoles, composition and use devices OREAL (FR) 1994-09-14 EP disclosed
WO-1994006406-A1 COSMETIC COMPOSITION CONTAINING SOLID ORGANIC ARTICLES COATED WITH A CATIONIC POLYMER L'OREAL (FR) 1994-03-31 WO disclosed
WO-1994006407-A1 COSMETIC COMPOSITION CONTAINING SOLID PARTICLES COATED WITH AN AMPHOTERIC POLYMER L'OREAL (FR) 1994-03-31 WO disclosed
EP-0425345-A1 Keratinic fibres dyeing process with amino-indoles, composition and use devices L'OREAL (FR) 1991-05-02 EP disclosed