Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
| ▸ | GLI2 | P10070 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827584 | 0.77 | AHR (0.50) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL31084784 | 0.77 | AHR (0.50) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL26312941 | 0.74 | MEN1 (0.47) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL7628593 | 0.73 | MAOA (0.49) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL11616880 | 0.73 | TERT (0.52) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL16466748 | 0.73 | APP (0.49) | MEN1KMT2AAPPMAPTL3MBTL1 | |
| SCHEMBL14487695 | 0.72 | ENPP2 (0.53) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL21318456 | 0.72 | NLRP3 (0.56) | TYRENPP2MEN1POLBMAPK1 | |
| SCHEMBL5480030 | 0.72 | SLC6A2 (0.46) | MEN1POLBMAPK1KMT2AAHR | |
| SCHEMBL27534535 | 0.70 | ENPP2 (0.50) | TYRENPP2MEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597022-B2 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | OREAL (FR) | 1999-11-17 | — | — | EP | claimed |
| EP-0587837-B1 | Cosmetic composition containing melanistic pigments in association with certain tocopherols, and method for protecting the skin, the hair, the mucous membranes and cosmetic compositions | OREAL (FR) | 1998-06-03 | — | — | EP | claimed |
| US-5752982-A | DYEING HAIR IN LIGHTFAST, WASHFAST COLORS | L'OREAL (FR) | 1998-05-19 | — | — | US | claimed |
| US-5695747-A | APPLYING TO THE SKIN OR HAIR AND ULTRAVIOLET PROETECTION AGENT | L'OREAL (FR) | 1997-12-09 | — | — | US | claimed |
| US-5670099-A | PREPARING A DISPERSION OF LIPIDIC VESICLES FROM ATLEAST ONE LIPID, AN AQUEOUS PHASE ENCAPSULATED IN VESICLE, DISSOLVING POLYMERIZABLE INDOLIC OR INDOLINIC MONOMER WITH A POLYMERIZATION AGENT, REACTS WITH MONOMER FORMS PARTICLES | L'OREAL (FR) | 1997-09-23 | — | — | US | claimed |
| US-5645609-A | Compositions which contain and processes which use an insoluble pigment obtained by the oxidative polymerization of indole derivatives for the temporary dyeing of keratinous fibers | L'OREAL (FR) | 1997-07-08 | — | — | US | claimed |
| EP-0575603-B1 | PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS | OREAL (FR) | 1996-10-23 | — | — | EP | claimed |
| US-5547658-A | Cosmetic composition containing melaninlike pigments in combination with certain tocopherols, and process for protecting the skin, hair, mucosae and cosmetic compositions | L'OREAL (FR) | 1996-08-20 | — | — | US | claimed |
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |
| EP-0605595-B1 | FINE DISPERSION OF MELANIC PIGMENTS, ITS PREPARATION AND UTILISATION IN COSMETICS | OREAL (FR) | 1995-12-06 | — | — | EP | claimed |
| US-5451254-A | Alcohols, esters, acids with melanin pigments for cosmetics | L'OREAL (FR) | 1995-09-19 | — | — | US | claimed |
| US-5449403-A | Product based on colored inorganic particles including a melanin pigment, process for its preparation and its use in cosmetics | L'OREAL (FR) | 1995-09-12 | — | — | US | claimed |
| EP-0518773-B1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | OREAL (FR) | 1995-02-08 | — | — | EP | claimed |
| EP-0467767-B1 | Product based on flaky particles containing melanine pigment and process for their preparation | OREAL (FR) | 1994-09-21 | — | — | EP | claimed |
| US-5205837-A | Formed in situ by oxidation of indole compound | L'OREAL (FR) | 1993-04-27 | — | — | US | claimed |
| US-5919469-A | Products derived from 2-imino-2,3-dihydro-1H-indoles, processes for their preparation, their use in cosmetics and cosmetic compositions using them | L'OREAL (FR) | 1999-07-06 | — | — | US | disclosed |
| US-5776497-A | OXIDATIVE POLYMERIZATION OF INDOLINE FOR COSMETICS | L'OREAL (FR) | 1998-07-07 | — | — | US | disclosed |
| US-5449403-A | Product based on colored inorganic particles including a melanin pigment, process for its preparation and its use in cosmetics | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5425993-A | Preparing lipid phase, contacting with aqueous phase to be encapsulated in vesicles, adding dispersion aqueous phase and precursor of submicronic particles, adding solution of agent capable of transforming precursor into particles | L'OREAL (FR) | 1995-06-20 | — | — | US | disclosed |
| US-5205837-A | Formed in situ by oxidation of indole compound | L'OREAL (FR) | 1993-04-27 | — | — | US | disclosed |