Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244665 | 0.88 | GPR174 (0.39) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6908037 | 0.85 | KMT2A (0.43) | ALDH1A1HTTABCC9ABCC8KCNJ11 | |
| SCHEMBL7243013 | 0.85 | LMNA (0.44) | ALDH1A1HTTKMT2AMEN1CACNA1C | |
| SCHEMBL7234603 | 0.85 | ABCC9 (0.45) | ALDH1A1HTTABCC9ABCC8KCNJ11 | |
| SCHEMBL7242344 | 0.85 | ABCC9 (0.45) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7621012 | 0.85 | ABCC9 (0.43) | ALDH1A1HTTABCC9ABCC8KCNJ11 | |
| SCHEMBL7235703 | 0.84 | ABCC9 (0.47) | ALDH1A1HTTABCC9ABCC8KCNJ11 | |
| SCHEMBL6436430 | 0.84 | MEN1 (0.48) | ALDH1A1HTTABCC9ABCC8KCNJ11 | |
| SCHEMBL7626510 | 0.83 | ABCC9 (0.40) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7626088 | 0.82 | MAPT (0.40) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194429-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078768-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | claimed |