Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432942 | 0.91 | MAPK1 (0.46) | MAPK1MAPK3B3GNT2PARP1PIK3CA | |
| SCHEMBL6235396 | 0.89 | MEN1 (0.52) | B3GNT2MAPTTP53RXFP1GAA | |
| SCHEMBL6232314 | 0.86 | B3GNT2 (0.46) | MAPK1MAPK3B3GNT2PARP1PIK3CA | |
| SCHEMBL6233923 | 0.85 | NAMPT (0.46) | MAPK1MAPK3B3GNT2PARP1PIK3CA | |
| SCHEMBL7104616 | 0.85 | NAMPT (0.46) | MAPK1MAPK3B3GNT2PARP1MAPT | |
| SCHEMBL27605972 | 0.83 | B3GNT2 (0.44) | MAPK1MAPK3B3GNT2PARP1MAPT | |
| SCHEMBL6236712 | 0.82 | MEN1 (0.52) | B3GNT2MAPTTP53GAAALDH1A1 | |
| SCHEMBL6727454 | 0.82 | MEN1 (0.50) | B3GNT2MAPTTP53GAAALDH1A1 | |
| SCHEMBL6232533 | 0.81 | MEN1 (0.53) | B3GNT2MAPTTP53RXFP1GAA | |
| SCHEMBL6238482 | 0.81 | MEN1 (0.51) | B3GNT2MAPTTP53RXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | MAPK1 1676/4885MAPK3 1031/4885B3GNT2 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.