SCHEMBL7630171

SCHEMBL7630171

C=Cc1ccccc1OC=CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 1/20 0.33
NFE2L2 Q16236 3/20 0.32
TRPA1 O75762 1/20 0.32
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630160 1.00 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ACYP3A4NFE2L2
SCHEMBL28463282 0.80 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AHPGDTSHR
SCHEMBL2331789 0.79 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ACYP3A4NFE2L2
SCHEMBL5139573 0.75 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ANFE2L2HPGD
SCHEMBL9157736 0.74 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ACYP3A4NFE2L2
SCHEMBL4612140 0.74 PTGS2 (0.37) ALDH1A1KMT2ACYP3A4TSHRHTT
SCHEMBL4612135 0.74 PTGS2 (0.37) ALDH1A1KMT2ACYP3A4TSHRHTT
SCHEMBL29377009 0.74 NFE2L2 (0.55) ALDH1A1MEN1KMT2ACYP3A4NFE2L2
SCHEMBL14909 0.74 NFE2L2 (0.55) ALDH1A1MEN1KMT2ACYP3A4NFE2L2
SCHEMBL297297 0.73 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ACYP3A4NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451948-B1 (METH)ACRYLATE COMPONENT; A THERMAL RESISTANCE-CONFERRING COMPONENT INCLUDING POLYMERIZABLE AROMATIC MATERIALS HAVING AT LEAST ONE CLAISEN REARRANGABLE FUNCTIONAL GROUP; AND (C) A RADICAL CURE-INDUCING COMPOSITION. LOCTITE CORPORATION 2002-09-17 US disclosed
US-20020107349-A1 RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION LOCTITE CORPORATION 2002-08-08 US disclosed
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US disclosed
WO-2001014459-A1 RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION LOCTITE CORPORATION (US) 2001-03-01 WO disclosed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO disclosed
EP-0490588-B1 A method of forming high-temperature resistant polymers LOCTITE IRELAND LTD (IE) 1996-04-24 EP disclosed
EP-0490589-B1 Styryloxy compounds and polymers thereof LOCTITE IRELAND LTD (IE) 1995-03-08 EP disclosed
US-5141970-A Photocuring an ether-ring substituted styrene and heating the Claisen-rearranged product to crosslink LOCTITE (IRELAND) LIMITED (IE) 1992-08-25 US disclosed
EP-0490588-A1 A method of forming high-temperature resistant polymers LOCTITE (IRELAND) Ltd. (IE) 1992-06-17 EP disclosed
EP-0490589-A1 Styryloxy compounds and polymers thereof LOCTITE (IRELAND) Ltd. (IE) 1992-06-17 EP disclosed
US-5084490-A Polymers for use in surface coatings, films, inks, adhesives and seals LOCTITE (IRELAND) LIMITED (IE) 1992-01-28 US disclosed