SCHEMBL2331789

SCHEMBL2331789

C=COc1ccccc1C=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HPGD P15428 3/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
CYP3A4 P08684 1/20 0.33
NFE2L2 Q16236 3/20 0.32
TRPA1 O75762 1/20 0.32
SRC P12931 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5139573 0.82 ALDH1A1 (0.42) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL8625344 0.82 ALDH1A1 (0.57) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL3113317 0.82 ADRA2B (0.43) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL29592755 0.82 ADRA2B (0.43) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL7624061 0.80 ALDH1A1 (0.35) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL297297 0.80 ALDH1A1 (0.48) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL7630171 0.79 ALDH1A1 (0.39) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL7630160 0.79 ALDH1A1 (0.39) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL9157736 0.77 ALDH1A1 (0.39) ALDH1A1HPGDHTTSMN1; SMN2TSHR
SCHEMBL5049336 0.77 HPGD (0.62) ALDH1A1HPGDHTTSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107407882-B Photocurable/thermosetting resin composition, cured product thereof, and printed wiring board 太阳控股株式会社 2021-01-26 CN disclosed
CN-105122137-B Photosensitive resin composition, protective film or insulating film, touch panel, and method for producing same 东丽株式会社 2020-02-07 CN disclosed
EP-2970266-B1 1-PHENOXY-3-(ALKYLAMINO)-PROPAN-2-OL DERIVATIVES AS CARM1 INHIBITORS AND USES THEREOF EPIZYME INC (US) 2018-01-31 EP disclosed
US-20170056389-A1 5-AMINOPYRAZOLE-4-CARBOXAMIDE INHIBITORS OF CDPK1 FROM T. GONDII AND C. PARVUM UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2017-03-02 US disclosed
US-20110198730-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION 2011-08-18 US disclosed
JP-2004352875-A INTERLAYER INSULATING FILM-FORMING RESIN COMPOSITION NAMICS CORP 2004-12-16 JP disclosed
JP-2004354737-A RESIN COMPOSITION FOR SOLDER RESIST NAMICS CORP 2004-12-16 JP disclosed
US-5373032-A Hardness, flexible, wear and chemical resistant protective coatings ISP INVESTMENTS INC. (US) 1994-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170056389-A1 5-AMINOPYRAZOLE-4-CARBOXAMIDE INHIBITORS OF CDPK1 FROM T. GONDII AND C. PARVUM PCK1, DCK, CILK1 ALDH1A1 4033/4885HPGD 2778/4885HTT 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.