Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061385 | 0.83 | CYP2A6 (0.38) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL7637891 | 0.81 | HPRT1 (0.39) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL7054875 | 0.81 | ENPP3 (0.38) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL1825938 | 0.80 | CYP2A6 (0.36) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL7200227 | 0.78 | KDM4E (0.34) | CYP3A4ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL9249191 | 0.72 | ALDH1A1 (0.41) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL6244475 | 0.72 | ALDH1A1 (0.37) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL7629651 | 0.72 | HPRT1 (0.45) | HPRT1CYP3A4ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL3149399 | 0.72 | ENPP3 (0.38) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL3144749 | 0.71 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991674-B1 | CYCLOPENTA[I]PHENANTHRENE METAL COMPLEX CATALYST SYSTEMS | BASF AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-6284851-B1 | Cyclopenta[I] phenanthrene-metal complex catalyst systems | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |