Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638274 | 0.93 | MAPT (0.37) | MAPTTLR8ALDH1A1LMNAHTT | |
| SCHEMBL7640024 | 0.92 | TLR8 (0.37) | ADORA3ADORA2AMAPTTLR8ALDH1A1 | |
| SCHEMBL7117214 | 0.91 | TLR8 (0.33) | ADORA3ADORA2AMAPTTLR8ALDH1A1 | |
| SCHEMBL7636300 | 0.90 | NPC1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL7633102 | 0.90 | ADORA3 (0.36) | ADORA3ADORA2AMAPTADORA1TLR8 | |
| SCHEMBL7125112 | 0.90 | DNM2 (0.33) | MAPTTLR8ALDH1A1LMNACDK1 | |
| SCHEMBL7117880 | 0.90 | DNM2 (0.33) | MAPTTLR8ALDH1A1LMNACDK1 | |
| SCHEMBL7117869 | 0.90 | DNM2 (0.33) | MAPTTLR8ALDH1A1LMNACDK1 | |
| SCHEMBL7121610 | 0.90 | DNM2 (0.33) | MAPTTLR8ALDH1A1LMNACDK1 | |
| SCHEMBL7121624 | 0.90 | DNM2 (0.33) | MAPTTLR8ALDH1A1LMNACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455054-B2 | THERAPY FOR SKIN DISORDERS | SOCIETE L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | claimed |
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | claimed |
| US-6455054-B2 | THERAPY FOR SKIN DISORDERS | SOCIETE L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | disclosed |
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051139-A1 | TREATING SKIN AFFLICTIONS/CONDITIONS WITH 2-AMINO-4-ALKYLAMINOPYRIMIDINE 3-OXIDE COMPOUNDS | TPMT, IL33, PTGS2 | ADORA3 38/4885ADORA2A 31/4885MAPT 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.