Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174346 | 0.83 | HPGD (0.49) | CTBP2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL7324963 | 0.80 | PAM (0.59) | FNTAFNTBCTBP2LMNARAB9A | |
| SCHEMBL10763072 | 0.78 | LMNA (0.53) | FNTAFNTBLMNAPTGS1 | |
| SCHEMBL24164778 | 0.78 | HTT (0.59) | CTBP2LMNANPC1RAB9AKDM4E | |
| SCHEMBL25457987 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL24476689 | 0.76 | CTBP2 (0.51) | CTBP2LMNAKDM4ECYP3A4HIF1A | |
| SCHEMBL7326010 | 0.75 | GSK3B (0.53) | NPC1RAB9A | |
| SCHEMBL1808490 | 0.75 | SMN1; SMN2 (0.54) | CA2KDM4E | |
| SCHEMBL4455 | 0.75 | CA2 (0.62) | CA2CAMK2AFNTAFNTBCTBP2 | |
| SCHEMBL7150590 | 0.74 | CA2 (0.68) | CA2CAMK2AFNTAFNTBCTBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |