Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714928 | 0.91 | FFAR1 (0.54) | MAOAMAOBBCHEFFAR1SIRT2 | |
| SCHEMBL10498077 | 0.89 | KCNA3 (0.59) | DRD2DRD4DRD3BCHEFFAR1 | |
| SCHEMBL8862908 | 0.88 | MAOA (0.50) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL7630360 | 0.86 | DRD2 (0.51) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL5542506 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL9026456 | 0.82 | MGLL (0.50) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL8862906 | 0.82 | MGLL (0.50) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL3028864 | 0.82 | MGLL (0.50) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL24041871 | 0.81 | CYP4F2 (0.71) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL2207165 | 0.81 | MAOA (0.53) | DRD2DRD4DRD3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1004304-A1 | COMPOSITION CONTAINING ASCORBIC ACID | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |