Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052902 | 0.81 | CYP1A2 (0.43) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL3839323 | 0.76 | EPHX1 (0.42) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL9771947 | 0.76 | TAAR1 (0.54) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL1256615 | 0.75 | SIGMAR1 (0.58) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL412663 | 0.75 | SIGMAR1 (0.58) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL4448592 | 0.75 | KIF11 (0.39) | CYP2D6CYP1A2OPRK1KCNH2 | |
| SCHEMBL28382981 | 0.75 | CSNK1E (0.39) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL9246750 | 0.73 | CYP1A2 (0.37) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL13006663 | 0.73 | SIGMAR1 (0.56) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL13189946 | 0.73 | SIGMAR1 (0.56) | TRPA1TAAR1SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916679-B1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-0916679-A1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1999-05-19 | — | — | EP | disclosed |