Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864463 | 0.79 | EPHX1 (0.43) | CYP1A2EPHX1SRRALPIPKM | |
| SCHEMBL4450220 | 0.76 | EPHX1 (0.40) | CYP1A2EPHX1SRRALPIPKM | |
| SCHEMBL30864312 | 0.75 | SRR (0.40) | CYP1A2EPHX1SRRTRPA1ALPI | |
| SCHEMBL14775501 | 0.75 | CYP1A2 (0.46) | CYP1A2EPHX1SRRALPIPKM | |
| SCHEMBL8147116 | 0.75 | CYP1A2 (0.46) | CYP1A2EPHX1SRRALPIPKM | |
| SCHEMBL9052902 | 0.75 | CYP1A2 (0.43) | CYP1A2EPHX1SRRTRPA1ALPI | |
| SCHEMBL7632637 | 0.73 | TRPA1 (0.48) | CYP1A2EPHX1TRPA1SLC6A2TAAR1 | |
| SCHEMBL8376755 | 0.72 | ALDH1A1 (0.44) | CYP1A2SRRALPIPKMPTGS1 | |
| SCHEMBL15578515 | 0.72 | ACE (0.53) | CYP1A2EPHX1SRRTRPA1ALPI | |
| SCHEMBL9091613 | 0.72 | TRPA1 (0.36) | CYP1A2EPHX1SRRTRPA1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369814-B1 | Thermoplastic resin composition | SUMITOMO CHEMICAL CO (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5159004-A | Polyphenylene ether, propylene polymer, rubbery substance, styrene resin, low molecular weight hydrocarbon resin and white oil and-or liquid parattin | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0369814-A2 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-23 | — | — | EP | disclosed |