Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7632809

CCCCC[Tl+].O=C([O-])C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.48
CES1 P23141 9/20 0.47
CES2 O00748 7/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrapentylammonium SCHEMBL15355495 0.78 SLC22A1 (0.52) FAAHCES1CES2MEN1CYP1A2
Tetrabuthylammonium SCHEMBL107845 0.78 SLC22A1 (0.52) FAAHCES1CES2MEN1CYP1A2
Tetrahexylammonium SCHEMBL15355454 0.77 SLC22A1 (0.54) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL6736795 0.76 CES2 (0.45) FAAHCES1CES2MEN1CYP1A2
Decanoic Acid SCHEMBL6565571 0.75 FAAH (0.59) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL2552104 0.75 FAAH (0.48) FAAHCES1CES2MEN1CYP1A2
Heptanoate SCHEMBL6563286 0.75 FAAH (0.59) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL11435310 0.75 DNM1 (0.54) FAAHCES1CES2MEN1CYP1A2
Myristic Acid SCHEMBL6563262 0.75 FAAH (0.59) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL3777644 0.75 DNM1 (0.54) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6417384-B1 SUPERIOR IMAGING AND VISUALIZATION OF NEOPLASTIC LESIONS; TUMOR-SPECIFIC CYTOTOXIC CANCER THERAPY, DIAGNOSIS AND TREATMENT THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2002-07-09 US disclosed
US-20020065429-A1 Radioiodinated phospholipid ether analogs and methods of using the same THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2002-05-30 US disclosed
US-6255519-B1 RADIOLABELLED PHARMACEUTICALS AND BIOLOGICAL PROBES UEFUL IN CANCER DIAGNOSIS AND TREATMENT; IMAGING TECHNOLOGY REGENTS OF THE UNIVERSITY OF MICHIGAN 2001-07-03 US disclosed
EP-0648130-B1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING UNIV MICHIGAN (US) 1998-12-30 EP disclosed
US-5795561-A TUMOR SPECIFIC; MEDICAL DIAGNOSIS THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1998-08-18 US disclosed
WO-1998024480-A1 RADIOIODINATED PHOSPHOLIPID ETHER ANALOGS AND METHODS OF USING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1998-06-11 WO disclosed
EP-0648130-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1995-04-19 EP disclosed
US-5347030-A Radioiodinated phospholipid ether analogues and methods of using same THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1994-09-13 US disclosed
EP-0648130-A4 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. UNIV MICHIGAN (US) 1994-01-26 EP disclosed
US-5093042-A Site-specific for liver; diagnosis of metastatic cancer THE UNIVERSITY OF MICHIGAN (US) 1992-03-03 US disclosed
US-5087721-A Tumor-specific; for diagnosis and therapy THE UNIVERSITY OF MICHIGAN (US) 1992-02-11 US disclosed
US-5077035-A Scintigraphic imaging of brain; Alzheimer*s diagnosis THE UNIVERSITY OF MICHIGAN (US) 1991-12-31 US disclosed
WO-1991017776-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1991-11-28 WO disclosed
US-4965391-A Tumor specific THE UNIVERSITY OF MICHIGAN (US) 1990-10-23 US disclosed
US-4957729-A CONTRAST THE UNIVERSITY OF MICHIGAN (US) 1990-09-18 US disclosed
US-4933157-A IMAGING AGENTS FOR ADRENAL GLANDS THE UNIVERSITY OF MICHIGAN (US) 1990-06-12 US disclosed
US-4925649-A Radioiodinated diacylglycerol analogues and methods of use THE UNIVERSITY OF MICHIGAN (US) 1990-05-15 US disclosed
US-4873075-A SITE-SPECIFIC TO LIVER AND HEPATOCYTE; SCINTIGRAPHY IMAGING THE UNIVERSITY OF MICHIGAN (US) 1989-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065429-A1 Radioiodinated phospholipid ether analogs and methods of using the same PHOSPHO1, CDIPT, LPCAT3 FAAH 1181/4885CES1 624/4885CES2 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.