Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241941 | 0.70 | ALDH1A1 (0.31) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL20088851 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL6209213 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL3398815 | 0.65 | ALDH1A1 (0.36) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL6911340 | 0.64 | ALDH1A1 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL755432 | 0.64 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL7093744 | 0.63 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL6817759 | 0.63 | LMNA (0.32) | ALDH1A1 | |
| SCHEMBL6208646 | 0.62 | LMNA (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL12336906 | 0.61 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376728-B1 | OF ALKENYL MONOMERS | HERCULES INCORPORATED | 2002-04-23 | — | — | US | claimed |
| US-6376728-B1 | OF ALKENYL MONOMERS | HERCULES INCORPORATED | 2002-04-23 | — | — | US | disclosed |