SCHEMBL7093744

SCHEMBL7093744

CC(C)N=C1C=CC(=Nc2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
IDO1 P14902 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MPI P34949 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
KMT2A Q03164 1/20 0.32
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755432 0.82 ALDH1A1 (0.47) ALDH1A1MAPK1HTTIDO1MAPT
SCHEMBL15871310 0.82 ALDH1A1 (0.36) ALDH1A1MAPTKDM4EMPICACNA1B
SCHEMBL6208646 0.81 LMNA (0.33) ALDH1A1MAPK1HTTMEN1KMT2A
SCHEMBL19195735 0.80 RAB9A (0.38) ALDH1A1MAPK1HTTMAPTMEN1
SCHEMBL1241941 0.80 ALDH1A1 (0.31) ALDH1A1MAPK1LMNA
SCHEMBL13067055 0.78 LMNA (0.40) LMNA
SCHEMBL6817759 0.78 LMNA (0.32) ALDH1A1LMNA
SCHEMBL19450214 0.77 NOS3 (0.33) NOS3NOS1
SCHEMBL7634802 0.76
SCHEMBL14150195 0.76 LMNA (0.36) ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376728-B1 OF ALKENYL MONOMERS HERCULES INCORPORATED 2002-04-23 US claimed
EP-3854610-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2024-04-17 EP disclosed
US-11749466-B1 Light harvesting supercapacitor and method of preparation thereof KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-09-05 US disclosed
US-20210403684-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2021-12-30 US disclosed
EP-3854610-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2021-07-28 EP disclosed
EP-2743303-B1 SIDEWALL RUBBER COMPOSITION AND TIRE USING SAME SUMITOMO RUBBER IND (JP) 2020-03-18 EP disclosed
EP-3118250-B1 RUBBER COMPOSITION FOR TIRE, PNEUMATIC TIRE, AND METHOD FOR MANUFACTURING RUBBER COMPOSITION FOR TIRE SUMITOMO RUBBER IND (JP) 2019-07-03 EP disclosed
US-10294349-B2 Rubber composition for tire, pneumatic tire, and method for manufacturing rubber composition for tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-21 US disclosed
EP-3012290-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-09-05 EP disclosed
EP-3012118-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
US-20140202609-A1 RUBBER COMPOSITION FOR SIDEWALL AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-24 US disclosed
EP-2743303-A1 SIDEWALL RUBBER COMPOSITION AND TIRE USING SAME Sumitomo Rubber Industries, Ltd. (JP) 2014-06-18 EP disclosed
US-7846884-B2 Lubricating oil compositions CHEMTURA CORPORATION (US) 2010-12-07 US disclosed
US-7846884-B2 Lubricating oil compositions CHEMTURA CORPORATION (US) 2010-12-07 US disclosed
US-20070123438-A1 Lubricating oil compositions LANXESS SOLUTIONS US INC. 2007-05-31 US disclosed
US-20070123438-A1 Lubricating oil compositions LANXESS SOLUTIONS US INC. 2007-05-31 US disclosed
US-6608225-B1 Esterification of alkali metal acrylate with a 3-chloroiso-butylalkoxysilane; adhesion promoters, protective coatings DEGUSSA AG (DE) 2003-08-19 US disclosed
US-6376728-B1 OF ALKENYL MONOMERS HERCULES INCORPORATED 2002-04-23 US disclosed
US-6147239-A Process for preparing n, n'-disubstituted p-quinonediimines, their use and organosilanes containing methacryloxy or acryloxy groups, processes for their stabilization and their preparation HUELS AKTIENGESELLSCHAFT (DE) 2000-11-14 US disclosed
US-5856542-A Process for preparing N,N'-disubstituted P-quinonediimines, their use and organosilanes containing methacryloxy or acryloxy groups, processes for their stabilization and their preparation HUELS AKTIENGESELLSCHAFT (DE) 1999-01-05 US disclosed