Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251336 | 0.94 | NAAA (0.48) | ALDH1A1CA2MAPK1HCAR2TSHR | |
| SCHEMBL28070253 | 0.92 | MAPT (0.55) | ALDH1A1ATMHCAR2MAPTGPR84 | |
| SCHEMBL10520107 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CA2ATMMAPK1HCAR2 | |
| SCHEMBL28447565 | 0.92 | CA2 (0.47) | ALDH1A1CA2ATMMAPK1HCAR2 | |
| SCHEMBL2276735 | 0.91 | ALDH1A1 (0.54) | ALDH1A1CA2ATMMAPK1HCAR2 | |
| SCHEMBL2123199 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CA2ATMMAPK1HCAR2 | |
| SCHEMBL25185273 | 0.88 | MAPT (0.55) | HCAR2TSHRMAPTGPR84NAAA | |
| SCHEMBL10523806 | 0.88 | MAPT (0.55) | HCAR2TSHRMAPTGPR84NAAA | |
| SCHEMBL4949251 | 0.88 | MAPT (0.55) | HCAR2TSHRMAPTGPR84NAAA | |
| SCHEMBL28651223 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CA2ATMMAPK1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787975-B2 | Cyanoacrylic adhesive compositions with improved resistance to high temperatures | PERMABOND ENGINEERING ADHESIVES LTD (GB) | 2023-10-17 | — | — | US | disclosed |
| CN-111205463-B | Polysiloxane skeleton polymer, photosensitive resin composition, pattern forming method and manufacturing of optical semiconductor device | 信越化学工业株式会社 | 2023-02-14 | — | — | CN | disclosed |
| CN-112272687-B | Phosphate amine salt composition, phosphate amine salt flame retardant composition, flame-retardant synthetic resin composition containing same, and molded article thereof | 株式会社ADEKA | 2022-06-10 | — | — | CN | disclosed |
| US-20200407596-A1 | CYANOACRYLIC ADHESIVE COMPOSITIONS WITH IMPROVED RESISTANCE TO HIGH TEMPERATURES | PERMABOND ENGINEERING ADHESIVES LTD (GB) | 2020-12-31 | — | — | US | disclosed |
| CN-102026966-B | Novel amino acid derivatives, preparation method and therapeutic use thereof | PHARMALEADS | 2014-02-12 | — | — | CN | disclosed |
| CN-102026966-A | Novel amino acid derivatives, preparation method and therapeutic use thereof | PHARMALEADS | 2011-04-20 | — | — | CN | disclosed |
| EP-1003707-B1 | MALONIC ACID AND ESTERS THEREOF | TRIKEM SA (BR) | 2002-12-04 | — | — | EP | disclosed |
| US-6395931-B1 | REACTION OF CYANOACETIC ACID WITH HYDROCHLORIC ACID TO FORM MALONIC ACID, SEPARATION OF ACETIC ACID BY-PRODUCTS AND PURIFICATION | TRIKEM S.A. (BR) | 2002-05-28 | — | — | US | disclosed |
| EP-1003707-A1 | MALONIC ACID AND ESTERS THEREOF | Trikem S.A. (BR) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008988-A1 | MALONIC ACID AND ESTERS THEREOF | TRIKEM S.A. (BR) | 1999-02-25 | — | — | WO | disclosed |
| US-5221760-A | Intermediates, leukotriene antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0341551-B1 | ALKENOIC ACID DERIVATIVES | BAYER AG (DE) | 1992-04-01 | — | — | EP | disclosed |
| US-5041638-A | Leucotriene antagonist; treatment of respiratory system disorders, cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0341551-A1 | Alkenoic acid derivatives | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |