Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996533 | 0.95 | GSR (0.44) | ALDH1A1ATMHCAR2MAPTCPB2 | |
| SCHEMBL9832203 | 0.95 | NAAA (0.43) | ALDH1A1HCAR2TSHRMAPTCPB2 | |
| SCHEMBL7449124 | 0.93 | MAPT (0.44) | ALDH1A1MAPTCPB2GSR | |
| SCHEMBL5983037 | 0.91 | ALDH1A1 (0.45) | ALDH1A1ATMHCAR2TSHRMAPT | |
| SCHEMBL9830216 | 0.90 | MAPT (0.44) | HCAR2MAPTCPB2NOD1GSR | |
| SCHEMBL7633731 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ATMHCAR2TSHRMAPT | |
| SCHEMBL9184074 | 0.88 | MAPT (0.47) | HCAR2MAPTCPB2NOD1 | |
| SCHEMBL9362410 | 0.88 | MAPT (0.47) | HCAR2MAPTCPB2NOD1 | |
| SCHEMBL28070253 | 0.85 | MAPT (0.55) | ALDH1A1ATMHCAR2MAPT | |
| SCHEMBL10520107 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ATMHCAR2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443136-A1 | NOVEL PEPTIDE DERIVATIVES FOR TREATMENT, PREVENTION OR ALLEVIATION OF A CONDITION ASSOCIATED WITH BONE LOSS OR LOW BONE DENSITY OR TO INHIBIT OSTEOCLAST DIFFERENTIATION AND STIMULATION | Neobiotics AB (SE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010147547-A1 | NOVEL PEPTIDE DERIVATIVES FOR TREATMENT, PREVENTION OR ALLEVIATION OF A CONDITION ASSOCIATED WITH BONE LOSS OR LOW BONE DENSITY OR TO INHIBIT OSTEOCLAST DIFFERENTIATION AND STIMULATION | NEOBIOTICS AB (SE) | 2010-12-23 | — | — | WO | disclosed |
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |
| EP-0617705-A4 | NON-PEPTIDIC SURROGATES OF THE ARG-GLY-ASP SEQUENCE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM. | YEDA RES & DEV (IL) | 1994-12-28 | — | — | EP | disclosed |
| EP-0617705-A1 | NON-PEPTIDIC SURROGATES OF THE ARG-GLY-ASP SEQUENCE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM. | YEDA RES & DEV (IL) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993009795-A1 | NON-PEPTIDIC SURROGATES OF THE ARG-GLY-ASP SEQUENCE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1993-05-27 | — | — | WO | disclosed |