Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125690 | 0.84 | GPR3 (0.38) | KDM4ESMN1; SMN2GPR3ALDH1A1LMNA | |
| SCHEMBL7195665 | 0.81 | GPR3 (0.40) | KDM4ESMN1; SMN2GPR3ALDH1A1LMNA | |
| SCHEMBL7127304 | 0.79 | ALDH1A1 (0.32) | ALDH1A1RAB9AMAPT | |
| SCHEMBL7633751 | 0.77 | DRD2 (0.35) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL4376916 | 0.69 | ALDH1A1 (0.48) | HTTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7116380 | 0.69 | DNMT1 (0.37) | RORARORCRORBALDH1A1MEN1 | |
| SCHEMBL7117683 | 0.67 | KDM4E (0.43) | HTTKDM4ECYP1A2ALDH1A1MEN1 | |
| SCHEMBL12083703 | 0.66 | RORC (0.56) | HTTKDM4ECYP1A2CYP2D6SLC2A1 | |
| SCHEMBL7124307 | 0.65 | GPR3 (0.41) | KDM4EGPR3ALDH1A1LMNAMAPT | |
| SCHEMBL7126885 | 0.65 | GPR3 (0.41) | KDM4ESMN1; SMN2GPR3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451724-B1 | BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-09-17 | — | — | US | disclosed |