Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455225 | 0.82 | PYCR1 (0.39) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL20832269 | 0.76 | PYCR1 (0.36) | PYCR1IDO1TSHRCYP1A2CYP1A1 | |
| SCHEMBL29446718 | 0.76 | CYP1A2 (0.48) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL97462 | 0.76 | TAAR1 (0.52) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL6299 | 0.76 | CYP1A2 (0.48) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| Methylamine SCHEMBL28202791 | 0.75 | PYCR1 (0.39) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL28135352 | 0.74 | CYP1A2 (0.46) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL5325998 | 0.73 | IDO1 (0.52) | PYCR1TAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL3645165 | 0.71 | TAAR1 (0.46) | PYCR1TAAR1TSHRCYP2A13HPGD | |
| SCHEMBL11516976 | 0.71 | APOBEC3G (0.43) | PYCR1TAAR1TSHRHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590722-B | Synthesis method of 2-trifluoromethyl benzofuran derivative | 温州大学 | 2022-11-04 | — | — | CN | disclosed |
| US-20200071322-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2020-03-05 | — | — | US | disclosed |
| CN-110590722-A | Synthesis method of 2-trifluoromethyl benzofuran derivative | 温州大学 | 2019-12-20 | — | — | CN | disclosed |
| US-6365779-B2 | OLEFIN POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2002-04-02 | — | — | US | disclosed |
| US-20010007044-A1 | Boratabenzene cocatalyst with metallocene catalyst | DEVORE DAVID D (US) | 2001-07-05 | — | — | US | disclosed |
| US-6255246-B1 | OLEFIN POLYMERIZATION | THE DOW CHEMICAL COMPANY | 2001-07-03 | — | — | US | disclosed |
| EP-0889911-B1 | METALLOCENE COCATALYST | DOW CHEMICAL CO (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0889911-A1 | METALLOCENE COCATALYST | THE DOW CHEMICAL COMPANY (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036937-A1 | METALLOCENE COCATALYST | THE DOW CHEMICAL COMPANY (US) | 1997-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071322-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | ITGB6, ITGA6, ITGAV | PYCR1 4590/4885TAAR1 4791/4885IDO1 4546/4885 |
| US-20010007044-A1 | Boratabenzene cocatalyst with metallocene catalyst | MFAP1, PFAS, FLNB | PYCR1 2609/4885TAAR1 1783/4885IDO1 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.