SCHEMBL7282207

SCHEMBL7282207

CCCCCOc1cccc([C]=O)c1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.57
▸ LTA4H P09960 2/20 0.53
▸ PLA2G4B P0C869 3/20 0.52
▸ SMPD1 P17405 3/20 0.51
▸ GGPS1 O95749 2/20 0.48
▸ KMT2A Q03164 1/20 0.47
▸ THRA P10827 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ NR5A1 Q13285 1/20 0.46
▸ NR1H4 Q96RI1 1/20 0.46
▸ GPBAR1 Q8TDU6 1/20 0.46
▸ TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7634664 0.98 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1GGPS1
SCHEMBL7756952 0.98 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1GGPS1
SCHEMBL9065483 0.98 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1GGPS1
SCHEMBL9065935 0.98 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1GGPS1
SCHEMBL9269275 0.98 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1GGPS1
SCHEMBL3029634 0.95 LTA4H (0.53) TSHRLTA4HPLA2G4BSMPD1KMT2A
SCHEMBL910595 0.90 KMT2A (0.54) TSHRLTA4HPLA2G4BKMT2ANR1H4
SCHEMBL10289405 0.83 TSHR (0.57) TSHRLTA4HPLA2G4BSMPD1
SCHEMBL910172 0.82 TP53 (0.53) TSHRLTA4HKMT2ATHRBTP53
SCHEMBL6960220 0.82 TSHR (0.59) TSHRLTA4HPLA2G4BSMPD1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 — — US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 — — US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 — — US disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 — — US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 — — US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 — — US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 — — US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 — — EP disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 — — EP disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 — — EP disclosed
US-5306719-A Cardiotonic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 — — US disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 — — EP disclosed
US-5162305-A Calcium lowering in blood; hypoglycemic agents, analgesics OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-10 — — US disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 — — US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 — — US disclosed
EP-0330241-A2 Calcitonin derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-08-30 — — EP disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B TSHR 1280/4885LTA4H 3853/4885PLA2G4B 3478/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 TSHR 1528/4885LTA4H 3146/4885PLA2G4B 2597/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 TSHR 1132/4885LTA4H 3708/4885PLA2G4B 3635/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 TSHR 3362/4885LTA4H 2477/4885PLA2G4B 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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