Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 11/20 | 0.67 |
| ▸ | LOX | P28300 | 10/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600459 | 0.92 | LOXL2 (0.67) | LOXL2LOXLMNAPGRKDR | |
| SCHEMBL3373348 | 0.84 | KCNK3 (0.74) | LOXL2LOXLMNAKCNK3KCNK9 | |
| SCHEMBL238350 | 0.82 | LOXL2 (0.59) | LOXL2LOX | |
| SCHEMBL4599769 | 0.81 | MITF (0.58) | LOXL2LOXMEN1KMT2A | |
| SCHEMBL18049113 | 0.81 | LOXL2 (1.00) | LOXL2LOX | |
| SCHEMBL18049198 | 0.80 | LOXL2 (1.00) | LOXL2LOX | |
| Hydrochloric Acid SCHEMBL18049284 | 0.80 | LOXL2 (1.00) | LOXL2LOX | |
| SCHEMBL31580448 | 0.80 | PGR (0.62) | LOXL2LOXLMNAPGRKDR | |
| SCHEMBL28439623 | 0.79 | KDM4E (0.55) | LOXL2LOXHTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL18049234 | 0.79 | LOXL2 (1.00) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806414-B1 | Intermediates for herbicidal carboxamide derivatives | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-1207154-A1 | Herbicidal carboxamide derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-0447004-B1 | Herbicidal carboxamide derivatives | SHELL INT RESEARCH (NL) | 1998-01-28 | — | — | EP | disclosed |
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | disclosed |
| US-5294597-A | 2-((Halophenyl)amido-)m,6-((halophenyl)oxy-)pyridines | SHELL RESEARCH LIMITED (GB) | 1994-03-15 | — | — | US | disclosed |
| EP-0447004-A2 | Herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-18 | — | — | EP | disclosed |
| US-4221715-A | Substituted dibenz[b,f][1,4]oxazepin-11-yl pyridinium salts and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221714-A | ANTI-PSYCHOTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-09-09 | — | — | US | disclosed |