Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632409 | 0.82 | FFAR1 (0.52) | SLC6A2SLC6A4SLC6A3ALDH1A1FFAR1 | |
| SCHEMBL7873209 | 0.82 | FNTA (0.46) | SLC6A2SLC6A4SLC6A3OPRK1ALDH1A1 | |
| SCHEMBL1456465 | 0.80 | SLC6A3 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1FFAR1 | |
| SCHEMBL7644430 | 0.80 | FFAR1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1FFAR1 | |
| SCHEMBL3901687 | 0.79 | CNR2 (0.44) | SLC6A2SLC6A3ALDH1A1FFAR1CASP1 | |
| SCHEMBL7873870 | 0.74 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3OPRK1ALDH1A1 | |
| SCHEMBL3274730 | 0.74 | CASP1 (0.41) | SLC6A2SLC6A3ALDH1A1PPARGPPARA | |
| SCHEMBL7871902 | 0.74 | ALDH1A1 (0.41) | SLC6A2SLC6A4SLC6A3OPRK1ALDH1A1 | |
| SCHEMBL9444866 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3FFAR1 | |
| SCHEMBL7925442 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433174-B1 | Process for producing novel naphthyridine derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1142892-A1 | PROCESSES FOR THE PREPARATION OF NOVEL NAPHTHYRIDINE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2001-10-10 | — | — | EP | disclosed |