Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873209 | 0.86 | FNTA (0.46) | ALDH1A1MAPK1L3MBTL1SLC6A3SLC6A2 | |
| SCHEMBL7873870 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1SLC6A3SLC6A2 | |
| SCHEMBL7871985 | 0.83 | SLC6A3 (0.44) | ALDH1A1MAPK1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8911597 | 0.79 | PRKCZ (0.48) | ALDH1A1KMO | |
| SCHEMBL7811343 | 0.77 | TACR1 (0.49) | SLC6A4NPSR1 | |
| SCHEMBL4471203 | 0.75 | TNF (0.48) | ALDH1A1SLC6A3SLC6A2SLC6A4KMO | |
| SCHEMBL6969734 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7870025 | 0.74 | SLC6A3 (0.39) | ALDH1A1MAPK1L3MBTL1SLC6A3SLC6A2 | |
| SCHEMBL7635176 | 0.74 | SLC6A2 (0.44) | ALDH1A1SLC6A3SLC6A2SLC6A4PPARG | |
| SCHEMBL28412325 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |