Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373324 | 0.78 | CYP2C9 (0.57) | PTGS2GAAMEN1KMT2APOLB | |
| SCHEMBL8066769 | 0.77 | HTR6 (0.58) | HTR6GAAKMT2AHSD11B1POLB | |
| SCHEMBL11676191 | 0.77 | CYTH2 (0.65) | HTR6GAAMEN1KMT2AGFER | |
| SCHEMBL13522250 | 0.77 | CA2 (0.56) | PTGS2GAAMEN1KMT2APOLB | |
| SCHEMBL5456564 | 0.76 | PTGS2 (0.45) | PTGS2GAAMEN1KMT2APOLB | |
| SCHEMBL8375609 | 0.76 | PTGS2 (0.48) | PTGS2GAAMEN1KMT2APOLB | |
| SCHEMBL4127736 | 0.76 | GLRA3 (0.53) | PTGS2HTR6GAAMEN1KMT2A | |
| SCHEMBL2858798 | 0.76 | ESR1 (0.55) | PTGS2GAAMEN1KMT2APOLB | |
| SCHEMBL15894599 | 0.76 | CYTH2 (0.59) | PTGS2HTR6GAAMEN1KMT2A | |
| SCHEMBL4710701 | 0.75 | CA2 (0.54) | PTGS2GAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015518-B1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SC HOLDING AG (CH) | 2002-05-15 | — | — | EP | disclosed |
| US-6323267-B1 | MIXING HIGH MOLECULAR WEIGHT ORGANIC OR INORGANIC MATERIAL WITH ISOXINDIGO COMPOUND | CIBA SPECIALTY CHEMICALS CORP. | 2001-11-27 | — | — | US | disclosed |
| EP-1015518-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | Ciba SC Holding AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999013007-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-03-18 | — | — | WO | disclosed |
| US-5192791-A | Antiinflammatory agents, immunomodulators, analgesics and antipyretics | BIOFOR, LTD. (US) | 1993-03-09 | — | — | US | disclosed |
| US-4959482-A | ANTIINFLAMMATORY, IMMUNOMODULATORY AND ANTIPYRETIC AGENTS, ANALGESICS | BIOFOR, LTD. (US) | 1990-09-25 | — | — | US | disclosed |
| US-4892870-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, IMMUNOMODULATING AGENTS | BIOFOR, LTD. (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0094422-B1 | SUBSTITUTED PYRIDINES | RIKER LABORATORIES, INCORPORATED (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0094425-B1 | 2,6-DI(T-BUTYL)-4-(2'-PYRROYL)PHENOL AND ANTIINFLAMMATORY COMPOSITIONS CONTAINING IT | RIKER LABORATORIES, INCORPORATED (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4535165-A | ANTIINFLAMMATORY, ANTIPYRETIC AGENTS, ANALGESICS, OXIDATION STABILIZERS OR ANTIBODY INHIBITORS | RIKER LABORATORIES, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4524210-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1985-06-18 | — | — | US | disclosed |
| US-4431831-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | RIKER LABORATORIES, INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4418074-A | 2,6 Di(t-butyl)-4-(2'-pyrrol)-phenol and anti-inflammatory use thereof | RIKER LABORATORIES, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0094422-A1 | SUBSTITUTED PYRIDINES. | RIKER LABORATORIES INC (US) | 1983-11-23 | — | — | EP | disclosed |
| EP-0094425-A1 | 2,6-Di(t-butyl)-4-(2'-pyrroyl)phenol and antiinflammatory compositions containing it. | RIKER LABORATORIES INC (US) | 1983-11-23 | — | — | EP | disclosed |
| US-4414217-A | ANTIINFLAMMATORY | RIKER LABORATORIES, INC. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0080356-A2 | Substituted furans | RIKER LABORATORIES, INC. (US) | 1983-06-01 | — | — | EP | disclosed |
| WO-1983001775-A1 | SUBSTITUTED PYRIDINES | RIKER LABORATORIES INC (US) | 1983-05-26 | — | — | WO | disclosed |
| WO-1983001774-A1 | SUBSTITUTED PYRROLE | RIKER LABORATORIES INC (US) | 1983-05-26 | — | — | WO | disclosed |
| US-4357345-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1982-11-02 | — | — | US | disclosed |