SCHEMBL7635660

SCHEMBL7635660

C=C[Si](C=C)(CC)c1ccc(C(=O)OO[CH]C(C)(C)C)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.32
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 3/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630997 0.91 PDK1 (0.32) RAB9APDK1PDK2PDK3PDK4
SCHEMBL7631467 0.87 ALDH1A1 (0.32) ALDH1A1TSHRHSD17B10TDP1THRA
SCHEMBL7634303 0.82 ALDH1A1 (0.34) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL7629376 0.82 NR1H2 (0.41) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL7628476 0.82 ESR1 (0.35) RAB9AMEN1NPC1MAPK1KMT2A
SCHEMBL7630284 0.82
SCHEMBL7630931 0.82 STAT3 (0.33) MAPTADRB2ADRB1ADRB3
SCHEMBL7626099 0.81 LMNA (0.34) RAB9AMEN1KMT2AHPGDALDH1A1
SCHEMBL7635518 0.81 LMNA (0.34) RAB9AMEN1KMT2AHPGDALDH1A1
SCHEMBL7632777 0.81 RAB9A (0.32) RAB9AMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed