Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954785 | 0.87 | LMNA (0.62) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL2477690 | 0.80 | LMNA (0.70) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL30486834 | 0.80 | LMNA (0.70) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5158052 | 0.80 | LMNA (0.79) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4801356 | 0.78 | LMNA (0.69) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12768028 | 0.78 | KEAP1 (0.81) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3257185 | 0.77 | KEAP1 (0.70) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL7213042 | 0.77 | LMNA (0.69) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL31106385 | 0.77 | KEAP1 (0.71) | LMNAHPGDALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL31106386 | 0.77 | KEAP1 (0.71) | LMNAHPGDALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |