Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451967 | 0.75 | ACHE (0.51) | ACHEMTNR1AMTNR1BHTR1AHTR2A | |
| SCHEMBL8854199 | 0.73 | ACHE (0.50) | ACHEMTNR1AMTNR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL6764862 | 0.71 | ACHE (0.49) | ACHEMTNR1AMTNR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL6764859 | 0.71 | ACHE (0.49) | ACHEMTNR1AMTNR1BHTR1AHTR2A | |
| SCHEMBL22581587 | 0.71 | ACHE (0.43) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL30733628 | 0.71 | ACHE (0.43) | ACHEHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL7639637 | 0.71 | MAPK1 (0.40) | MAPK1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29137337 | 0.71 | CYP3A4 (0.48) | ACHEMAPK1MEN1MAPTKMT2A | |
| SCHEMBL19590927 | 0.69 | PTGS2 (0.56) | MAPK1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5082503 | 0.69 | ACHE (0.46) | ACHEMTNR1AMTNR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832866-B1 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | BASELL POLYOLEFINE GMBH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0832866-A2 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | TARGOR GmbH (DE) | 1998-04-01 | — | — | EP | disclosed |