Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808605 | 0.89 | PTGS1 (0.62) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL2392519 | 0.87 | LDHA (0.49) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL18648672 | 0.86 | CYP3A4 (0.50) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL2391312 | 0.86 | TSHR (0.73) | LMNAGAAALDH1A1MAPK1TSHR | |
| SCHEMBL3616256 | 0.86 | ALDH1A1 (0.53) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL3659918 | 0.86 | GAA (0.50) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL30859524 | 0.85 | LMNA (0.63) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL11187045 | 0.85 | LMNA (0.63) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL17709374 | 0.85 | REN (0.49) | LMNAHTTNPC1GAAKMT2A | |
| SCHEMBL11281357 | 0.84 | PTGS1 (0.53) | LMNAHTTNPC1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024298-A | Tertiary amide compound containing naphthyl and its preparation method and application | 北京中医药大学 | 2023-11-10 | — | — | CN | claimed |
| WO-2023086696-A2 | APPARATUS AND METHODS FOR CONTINUOUS FLOW SYNTHESIS OF CISATRACURIUM | ODH IP Corp. (US) | 2023-05-19 | — | — | WO | claimed |
| CN-104829470-B | One is combined into the midbody compound of Ivabradine and its application | 江苏宇田医药有限公司 | 2017-08-25 | — | — | CN | claimed |
| CN-104829470-A | Set of intermediate compounds used for synthesis of Ivabradine, and applications thereof | JIANGSU YUTIAN PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-102924318-B | L-leucine derivatives blocking entrance of H5N1 avian influenza virus and preparation method for same | UNIV WUHAN | 2014-06-04 | — | — | CN | claimed |
| CN-102924318-A | L-leucine derivatives blocking entrance of H5N1 avian influenza virus and preparation method for same | UNIV WUHAN | 2013-02-13 | — | — | CN | claimed |
| CN-101643465-A | Preparation method of COMT inhibitor 5, 6, 7, 3', 4'-pentamethoxyl isoflavone | UNIV DONGHUA | 2010-02-10 | — | — | CN | claimed |
| EP-4582423-A1 | NOVEL TRICYCLIC DERIVATIVE COMPOUND AND USES THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2025-07-09 | — | — | EP | disclosed |
| CN-120077041-A | Tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-118027395-B | Coating material, preparation method and application thereof, and lithium battery diaphragm | 安徽壹石通材料科学研究院有限公司 | 2025-04-29 | — | — | CN | disclosed |
| US-20250066378-A1 | SPIRO-OXAZOLONES | HOFFMANN-LA ROCHE INC. (US) | 2025-02-27 | — | — | US | disclosed |
| US-12162887-B2 | Spiro-oxazolones | HOFFMANN-LA ROCHE INC. (US) | 2024-12-10 | — | — | US | disclosed |
| CN-118027395-A | Coating material, preparation method and application thereof, and lithium battery diaphragm | 安徽壹石通材料科学研究院有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-4232014-A | AMIDOALKYLINDANS | MARION LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4191770-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4181738-A | DOPAMINERGIC | CORNELL RESEARCH FOUNDATION, INC. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |
| US-3962254-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3950236-A | OXIDATION, ALKYL-ALKOXY-BIBENZYL COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162887-B2 | Spiro-oxazolones | AVPR1A, AVPR1B, AVPR2 | LMNA 3114/4885HTT 1513/4885NPC1 3185/4885 |
| US-20250066378-A1 | SPIRO-OXAZOLONES | AVPR1A, AVPR1B, AVPR2 | LMNA 3114/4885HTT 1513/4885NPC1 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.