Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016374 | 0.80 | RAB9A (0.51) | POLBMCOLN3ALDH1A1TSHRLMNA | |
| SCHEMBL7556703 | 0.80 | MCOLN3 (0.60) | POLBMCOLN3ALDH1A1TSHRKMT2A | |
| SCHEMBL7554619 | 0.79 | KMT2A (0.52) | POLBMCOLN3ALDH1A1TSHRLMNA | |
| SCHEMBL7638566 | 0.70 | LMNA (0.42) | GRIN1ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL7552508 | 0.70 | LMNA (0.39) | ALDH1A1TSHRLMNAKMT2AKDM4E | |
| SCHEMBL7555016 | 0.70 | ABL1 (0.41) | ALDH1A1TSHRLMNARAB9AKMT2A | |
| SCHEMBL27362505 | 0.68 | ABL1 (0.50) | ALDH1A1TSHRLMNARAB9AKMT2A | |
| SCHEMBL1015441 | 0.68 | MCL1 (0.52) | ALDH1A1RAB9ASMN1; SMN2MCL1 | |
| SCHEMBL22032806 | 0.68 | ALDH1A1 (0.59) | POLBMCOLN3ALDH1A1TSHRLMNA | |
| SCHEMBL7553332 | 0.68 | HTT (0.47) | POLBMCOLN3ALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369270-B1 | CHEMICAL INTERMEDIATES | RHONE POULENC AGRICULTURE LIMITED (GB) | 2002-04-09 | — | — | US | disclosed |