Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MECP2 | P51608 | 1/20 | 0.35 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313645 | 0.83 | HSD17B10 (0.39) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL7308323 | 0.79 | TSHR (0.37) | MEN1KMT2AP2RX7 | |
| SCHEMBL15952330 | 0.74 | CYP2A6 (0.42) | P2RX7 | |
| SCHEMBL18507295 | 0.73 | KMO (0.47) | MIFRAB9A | |
| SCHEMBL23505860 | 0.68 | KIF11 (0.36) | MEN1KMT2AMIFMAPTRAB9A | |
| SCHEMBL5059055 | 0.67 | NISCH (0.39) | MEN1KMT2ARAB9AP2RX7 | |
| SCHEMBL23019900 | 0.67 | ALDH1A1 (0.47) | MEN1KMT2AMAOBMAPTRAB9A | |
| SCHEMBL15951872 | 0.67 | KMT2A (0.38) | MEN1KMT2AMAOBLMNAMAPT | |
| SCHEMBL15952152 | 0.66 | KDM4E (0.41) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL23019907 | 0.65 | NPC1 (0.45) | MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |