Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313645 | 0.80 | HSD17B10 (0.39) | TSHRP2RX7MEN1GLAKMT2A | |
| SCHEMBL7638239 | 0.79 | MEN1 (0.43) | P2RX7MEN1KMT2A | |
| SCHEMBL7304049 | 0.76 | BCHE (0.40) | — | |
| SCHEMBL24181414 | 0.72 | GPR88 (0.31) | — | |
| SCHEMBL15952330 | 0.72 | CYP2A6 (0.42) | P2RX7 | |
| SCHEMBL23019900 | 0.68 | ALDH1A1 (0.47) | MEN1GAAKMT2A | |
| SCHEMBL18507295 | 0.68 | KMO (0.47) | GAA | |
| SCHEMBL15951872 | 0.65 | KMT2A (0.38) | TSHRMEN1GAAKMT2ANISCH | |
| SCHEMBL223709 | 0.65 | TSHR (0.68) | TSHRAPPMEN1GLAGAA | |
| SCHEMBL17283460 | 0.65 | TSHR (0.68) | TSHRAPPMEN1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |