Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7634422 | 0.87 | TSHR (0.33) | TSHRALDH1A1MAPT | |
| SCHEMBL7943317 | 0.83 | TSHR (0.33) | TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7632839 | 0.78 | APAF1 (0.33) | TSHRALDH1A1MAPT | |
| SCHEMBL7638394 | 0.76 | KMT2A (0.32) | MAPT | |
| Hydrochloric Acid SCHEMBL7632725 | 0.74 | APAF1 (0.33) | TSHRALDH1A1MAPT | |
| SCHEMBL7943322 | 0.72 | TSHR (0.34) | TSHRALDH1A1MAPT | |
| SCHEMBL7946701 | 0.72 | TSHR (0.34) | TSHRALDH1A1MAPT | |
| SCHEMBL7638323 | 0.70 | ALDH1A1 (0.34) | TSHRALDH1A1MAPT | |
| SCHEMBL7634428 | 0.70 | ALDH1A1 (0.34) | TSHRALDH1A1MAPT | |
| SCHEMBL7946696 | 0.70 | TSHR (0.33) | TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020098973-A1 | Bridged gallium or indium containing group 4 metal complexes | CAMPBELL RICHARD E (US) | 2002-07-25 | — | — | US | disclosed |
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |