Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946701 | 0.98 | TSHR (0.34) | TSHRMAPTALDH1A1CACNA1GAPAF1 | |
| SCHEMBL7638323 | 0.75 | ALDH1A1 (0.34) | TSHRMAPTALDH1A1APAF1TDP2 | |
| SCHEMBL7633241 | 0.73 | APAF1 (0.36) | TSHRMAPTALDH1A1APAF1TDP2 | |
| SCHEMBL7946696 | 0.73 | TSHR (0.33) | TSHRMAPTALDH1A1APAF1TDP2 | |
| SCHEMBL7943317 | 0.73 | TSHR (0.33) | TSHRMAPTALDH1A1APAF1TDP2 | |
| SCHEMBL7634428 | 0.73 | ALDH1A1 (0.34) | TSHRMAPTALDH1A1APAF1TDP2 | |
| Hydrochloric Acid SCHEMBL7638320 | 0.72 | TSHR (0.33) | TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7634422 | 0.72 | TSHR (0.33) | TSHRMAPTALDH1A1 | |
| SCHEMBL6910737 | 0.69 | DRD2 (0.40) | TSHRMAPTALDH1A1APAF1TDP2 | |
| Hydrochloric Acid SCHEMBL6865425 | 0.68 | DRD2 (0.32) | TSHRMAPTALDH1A1APAF1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |