Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410921 | 0.82 | TDP1 (0.41) | TDP1HTR7HTR1BLMNAL3MBTL1 | |
| SCHEMBL2863207 | 0.81 | ALDH1A1 (0.52) | TDP1MAPTALDH1A1GAALMNA | |
| Hydrochloric Acid SCHEMBL2863204 | 0.79 | ALDH1A1 (0.50) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL11671939 | 0.79 | HPGD (0.47) | MAPTALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL12772066 | 0.78 | TDP1 (0.36) | TDP1MAPTALDH1A1GAATP53 | |
| SCHEMBL15966175 | 0.78 | CYP1A2 (0.44) | TDP1MAPTHTR7HTR1BL3MBTL1 | |
| SCHEMBL9584860 | 0.77 | KDM4E (0.46) | TDP1MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12646498 | 0.76 | HTR7 (0.46) | TDP1MAPTALDH1A1GAATP53 | |
| SCHEMBL8740808 | 0.76 | HTR7 (0.42) | TDP1MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12774397 | 0.76 | MAPT (0.58) | TDP1MAPTGAAAPPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1004304-A1 | COMPOSITION CONTAINING ASCORBIC ACID | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |