SCHEMBL7639484

SCHEMBL7639484

C(C=Cc1ccccc1)=Cc1ccccc1.CC1=C2CCC3=C(C)C([Zr]C1c1cccc(-c4ccccc4)c12)c1cccc(-c2ccccc2)c13

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.34
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
HTR7 P34969 1/20 0.32
CYP11B2 P19099 3/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
CHRNA10 Q9GZZ6 1/20 0.31
CHRNA9 Q9UGM1 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672615 0.90 HTR1A (0.35) HTR1ADRD2HTR7CYP11B2CHRNB2
SCHEMBL1898930 0.82 MAOB (0.33) MAOB
SCHEMBL7930453 0.82 CHRNB2 (0.34) HTR1ADRD2HTR7CYP11B2CHRNB2
SCHEMBL1900079 0.70 PDCD1 (0.32) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL217236 0.70 PARP10 (0.35) HTR1ADRD2HTR7CYP11B2CHRNB2
Hydrochloric Acid SCHEMBL217523 0.70 HTR1A (0.36) HTR1ADRD2HTR7CYP11B2CHRNB2
SCHEMBL7599331 0.70 HTR1A (0.34) HTR1ADRD2HTR7CYP11B2ALDH1A1
SCHEMBL5345743 0.70 HTR1A (0.34) HTR1ADRD2HTR7CYP11B2CHRNB2
Chloromethane SCHEMBL7185377 0.68 PDCD1 (0.30)
SCHEMBL8852525 0.66 MAOB (0.44) MAOBALDH1A1CYP3A4CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6462156-B2 AS POLYMERIZATION CATALYST FOR PRODUCING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY 2002-10-08 US disclosed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US disclosed