Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672615 | 0.91 | HTR1A (0.35) | CHRNB2CHRNA4BRD4HRH1PDCD1 | |
| SCHEMBL7639484 | 0.82 | MAOB (0.34) | CHRNB2CHRNA4HTR1AHTR7DRD2 | |
| SCHEMBL1900079 | 0.78 | PDCD1 (0.32) | CHRNB2CHRNA4PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL218744 | 0.78 | HTR1A (0.34) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL219025 | 0.78 | CHRNB2 (0.33) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| Chloromethane SCHEMBL7185377 | 0.75 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL1898930 | 0.70 | MAOB (0.33) | — | |
| Hydrochloric Acid SCHEMBL217523 | 0.69 | HTR1A (0.36) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL217236 | 0.69 | PARP10 (0.35) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL7599331 | 0.69 | HTR1A (0.34) | CHRNB2CHRNA4BRD4PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153938-A1 | CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |