Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14532294 | 0.85 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2620993 | 0.85 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL506591 | 0.82 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9176879 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28411629 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27610369 | 0.81 | CLK1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL506620 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1060868 | 0.81 | DYRK1A (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2113508 | 0.81 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10230254 | 0.81 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059107-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-4310087-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| US-11827662-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11814379-B2 | Cyano quinoline amide compounds as HER2 inhibitors and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| WO-2023196875-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-3660014-B1 | ALKALOID DERIVATIVE HAVING ANGIOGENESIS INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SEOUL NAT UNIV R&DB FOUNDATION (KR) | 2023-08-30 | — | — | EP | disclosed |
| EP-3660014-B1 | ALKALOID DERIVATIVE HAVING ANGIOGENESIS INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SEOUL NAT UNIV R&DB FOUNDATION (KR) | 2023-08-30 | — | — | EP | disclosed |
| US-11701333-B2 | Antibacterial compounds | Kent Innovation & Enterprise (GB) | 2023-07-18 | — | — | US | disclosed |
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-6576765-B2 | Process for preparing amic acid esters | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5462850-A | Color photographic paper having reflective base, layers of photosensitive silver halide emulsions containing silver chloride or silver chlorobromide sensitized with specified cyanine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0287100-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0253390-B1 | PHOTOGRAPHIC SUPPORT AND COLOR PHOTOSENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4894321-A | SILVER HALIDE EMULSIONS, IMAGES, MULTILAYER | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| US-4851327-A | THIN SOLID METAL FILM | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4822726-A | HIGH SILVER CHLORIDE CONCENTRATION | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0287100-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-19 | — | — | EP | disclosed |
| EP-0253390-A2 | Photographic support and color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, CYP4F11, WEE1 | NPC1 718/4885RAB9A 3016/4885SMN1; SMN2 4769/4885 |
| US-11701333-B2 | Antibacterial compounds | ARF1, ARL1, TLR1 | NPC1 407/4885RAB9A 1656/4885SMN1; SMN2 3087/4885 |
| US-11814379-B2 | Cyano quinoline amide compounds as HER2 inhibitors and methods of use | ERBB2, EGFR, ERBB3 | NPC1 1439/4885RAB9A 3322/4885SMN1; SMN2 4549/4885 |
| US-11827662-B2 | Cot modulators and methods of use thereof | BRDT, THRB, HCCS | NPC1 4279/4885RAB9A 4028/4885SMN1; SMN2 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.