Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 3/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643240 | 0.85 | NPSR1 (0.55) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL7646542 | 0.84 | NPSR1 (0.40) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL7647135 | 0.81 | ALDH1A1 (0.41) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL7641009 | 0.81 | ALOX5 (0.39) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6913312 | 0.81 | LMNA (0.40) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6908555 | 0.78 | POLB (0.36) | NPSR1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL174224 | 0.74 | KMT2A (0.62) | KMT2AALDH1A1ESR1 | |
| SCHEMBL20981709 | 0.74 | HCRTR2 (0.43) | CDK1CCNB1CCNA2CCND1CDK2 | |
| SCHEMBL2575447 | 0.70 | KMT2A (0.47) | NPSR1KMT2AALDH1A1POLBHSD17B10 | |
| SCHEMBL27487172 | 0.70 | KMT2A (0.43) | NPSR1KMT2AALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |