SCHEMBL7640865

SCHEMBL7640865

C=Cc1ccnnc1Cc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.37
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LTB4R Q15722 2/20 0.34
CYP2C9 P11712 2/20 0.34
LMNA P02545 2/20 0.34
CYP1A2 P05177 2/20 0.34
PRNP P04156 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HTR2C P28335 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20767516 0.77 KDM4E (0.41) CALM1LTB4RMEN1KMT2AALDH1A1
SCHEMBL8781506 0.74 CALM1 (0.42) CALM1HTTNPSR1LTB4RCYP2C9
SCHEMBL28509588 0.73 ALDH1A1 (0.43) CALM1HTTNPSR1LTB4RCYP2C9
SCHEMBL29097522 0.73 CALM1 (0.41) CALM1HTTNPSR1LTB4RCYP2C9
SCHEMBL5382999 0.73 BCL2 (0.44) CALM1HTTNPSR1LTB4RCYP2C9
SCHEMBL11803638 0.69 CYP11B1 (0.42) CALM1KDM5BALDH1A1TAAR1
SCHEMBL7640856 0.68 CALM1 (0.39) CALM1HTTLTB4RCYP2C9LMNA
SCHEMBL20829977 0.67 ACVR2A (0.33) ALDH1A1
SCHEMBL163961 0.66 CALM1 (0.46) CALM1MEN1KMT2AALDH1A1HPGD
SCHEMBL10791795 0.66 CALM1 (0.46) CALM1NPSR1LMNAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325991-B2 All-acrylic multigraft copolymer superelastomers UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2022-05-10 US disclosed
US-20210108018-A1 ALL-ACRYLIC MULTIGRAFT COPOLYMER SUPERELASTOMERS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2021-04-15 US disclosed
WO-2018200671-A1 ALL-ACRYLIC MULTIGRAFT COPOLYMER SUPERELASTOMERS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-11-01 WO disclosed
EP-0764506-B1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KK (JP) 2002-01-02 EP disclosed
US-5961902-A Manufacturing method for molded multilayer article ARACO KABUSHIKI KAISHA (JP) 1999-10-05 US disclosed
EP-0764506-A1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KABUSHIKI KAISHA (JP) 1997-03-26 EP disclosed