SCHEMBL7638019

SCHEMBL7638019

C=C(C)c1cccc(OCOCC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAOB P27338 5/20 0.41
MEN1 O00255 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
RECQL P46063 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KAT6A Q92794 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
HTT P42858 1/20 0.39
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077874 0.86 KMT2A (0.54) KMT2ASMN1; SMN2LMNAMAPK1L3MBTL1
SCHEMBL5979083 0.86 MAOB (0.40) KMT2AMAOBF2PLGPRSS1
SCHEMBL7639971 0.83 MAOB (0.43) KMT2AMAOBPRSS1MAOA
SCHEMBL7640912 0.81 PARP10 (0.43) KMT2ALMNAL3MBTL1MAOBMEN1
SCHEMBL5036731 0.79 KMT2A (0.55) KMT2AMAPK1KAT6ANR1H4PRSS1
SCHEMBL5033472 0.77 SMPD1 (0.61) KMT2ANR1H4PRSS1
SCHEMBL1665107 0.77 TP53 (0.47) SMN1; SMN2LMNAMAPK1L3MBTL1MAOB
SCHEMBL8067261 0.77 ALDH1A1 (0.50) KMT2AMAOBALDH1A1RECQLF2
SCHEMBL23975528 0.76 CHRNB2 (0.53) TP53CYP3A4
SCHEMBL23907052 0.76 TP53 (0.43) KMT2ALMNAMAPK1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465150-B1 COMPRISING AN AROMATIC SULFONIC ACID ONIUM SALT COMPOUND ACID GENERATOR, FOR EXAMPLE, 2,4-DIFLUOROBENZENESULFONIC ACID ANION AND AN ONIUM CATION OF SULFUR OR IODONIUM, AND A COPOLYMER REPRESENTED BY 4-HYDROXYSTYRENE/4-T-BUTOXYSTYRENE COPOLYMER JSR CORPORATION (JP) 2002-10-15 US claimed
US-6465150-B1 COMPRISING AN AROMATIC SULFONIC ACID ONIUM SALT COMPOUND ACID GENERATOR, FOR EXAMPLE, 2,4-DIFLUOROBENZENESULFONIC ACID ANION AND AN ONIUM CATION OF SULFUR OR IODONIUM, AND A COPOLYMER REPRESENTED BY 4-HYDROXYSTYRENE/4-T-BUTOXYSTYRENE COPOLYMER JSR CORPORATION (JP) 2002-10-15 US disclosed