Guaiacol

Guaiacol

SCHEMBL7640932

COc1ccccc1O.Cc1cccc(O)c1O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.69
CA2 P00918 3/20 0.69
TP53 P04637 2/20 0.69
TSHR P16473 1/20 0.69
ALDH1A1 P00352 4/20 0.67
LMNA P02545 2/20 0.67
HPGD P15428 2/20 0.67
ALOX15 P16050 2/20 0.67
HSD17B10 Q99714 2/20 0.67
KDM4E B2RXH2 2/20 0.67
MAPT P10636 2/20 0.67
CYP3A4 P08684 1/20 0.67
ALOX12 P18054 1/20 0.67
MAPK1 P28482 1/20 0.67
TRPA1 O75762 2/20 0.65
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dimethoxybenzene SCHEMBL27632099 0.94 ALDH1A1 (0.69) CA1CA2TP53TSHRALDH1A1
Guaiacol SCHEMBL14921410 0.88 CA1 (0.82) CA1CA2TP53TSHRALDH1A1
Guaiacol SCHEMBL8023631 0.86 CA1 (0.78) CA1CA2TP53TSHRALDH1A1
Methoxymethane SCHEMBL27763536 0.83 TRPA1 (0.85) CA1CA2TP53TSHRALDH1A1
Guaiacol SCHEMBL21626 0.83
Guaiacol SCHEMBL671733 0.83 CA2 (1.00) CA1CA2TP53TSHRALDH1A1
Guaiacol SCHEMBL29454477 0.83
SCHEMBL50085 0.81 ALDH1A1 (0.67) CA1CA2TP53TSHRALDH1A1
SCHEMBL29661990 0.81 ALDH1A1 (0.67) CA1CA2TP53TSHRALDH1A1
Guaiacol SCHEMBL25403512 0.81 CA2 (0.95) CA1CA2TP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6439709-B1 Method for reducing cavitation in impulse ink jet printing device TRIDENT INTERNATIONAL, INC. 2002-08-27 US claimed
EP-3624596-A1 METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD International Flavors & Fragrances Inc. (US) 2020-03-25 EP disclosed
WO-2018213154-A1 METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-11-22 WO disclosed
CN-101538474-B Method for preparing pyroligneous by utilizing apricot shells UNIV NORTHWEST A&F 2013-06-05 CN disclosed
CN-101538474-A Method for preparing wood vinegar from apricot shells UNIV NORTHWEST A&F 2009-09-23 CN disclosed
US-6439709-B1 Method for reducing cavitation in impulse ink jet printing device TRIDENT INTERNATIONAL, INC. 2002-08-27 US disclosed