Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872863 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL24666581 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20012332 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1RAB9A | |
| SCHEMBL26271105 | 0.73 | KMT2A (0.45) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13377767 | 0.73 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13460706 | 0.73 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13377755 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6283595 | 0.71 | L3MBTL1 (0.50) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14278239 | 0.71 | CNR2 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21522983 | 0.71 | RAB9A (0.46) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6075143-A | USEFUL FOR FORMING PEPTIDE NUCLEIC ACIDS OR HYBRID OF PEPTIDE NUCLEIC ACIDS AND DEOXYNUCLEIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |