Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640992 | 0.88 | MEN1 (0.47) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL6283595 | 0.83 | L3MBTL1 (0.50) | ALDH1A1KDM4EPTGDR2MEN1KMT2A | |
| SCHEMBL20012332 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TK1MEN1KMT2AHPGD | |
| SCHEMBL26271105 | 0.77 | KMT2A (0.45) | ALDH1A1KDM4ETK1MEN1KMT2A | |
| SCHEMBL19873745 | 0.76 | MCL1 (0.36) | PTGDR2MEN1KMT2AMAPT | |
| SCHEMBL30178343 | 0.76 | MCL1 (0.36) | PTGDR2MEN1KMT2AMAPT | |
| SCHEMBL13377755 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TK1MEN1KMT2A | |
| SCHEMBL13377767 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TK1MEN1KMT2A | |
| SCHEMBL13460706 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TK1MEN1KMT2A | |
| SCHEMBL17870790 | 0.73 | CDK9 (0.38) | ALDH1A1KDM4EMEN1KMT2AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |