Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408066 | 0.88 | XIAP (0.55) | XIAPSMN1; SMN2MAPTTP53LMNA | |
| SCHEMBL7644396 | 0.84 | XIAP (0.43) | XIAPSMN1; SMN2MAPTTP53CIT | |
| SCHEMBL7642932 | 0.79 | XIAP (0.34) | XIAPSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7637784 | 0.78 | XIAP (0.43) | XIAPSMN1; SMN2MAPTPIK3CDPIK3CA | |
| SCHEMBL7643043 | 0.77 | LNPEP (0.42) | XIAPCIT | |
| Hydrochloric Acid SCHEMBL7403586 | 0.77 | RAB9A (0.41) | XIAPSMN1; SMN2MAPTTP53LMNA | |
| SCHEMBL7408062 | 0.76 | XIAP (0.37) | XIAPSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7406241 | 0.73 | L3MBTL1 (0.36) | XIAPSMN1; SMN2MAPTLMNANPC1 | |
| Hydrochloric Acid SCHEMBL7403583 | 0.72 | L3MBTL1 (0.36) | XIAPSMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL8195939 | 0.71 | GAA (0.40) | SMN1; SMN2MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468977-B1 | COMPOUNDS USEFUL IN TREATMENT TREATMENT OF DISORDER AND/OR DISEASE CAUSED BY ACTIVITY OF ENZYMES SUCH AS HUMAN RHINOVIRUS 3C PROTEASE, TRANSGLUTAMINASE AND CATHEPSINS | APOTEX INC. (CA) | 2002-10-22 | — | — | US | disclosed |