Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27537901 | 0.97 | PDCD1 (0.35) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| Fluoride Ion SCHEMBL27638234 | 0.80 | PDCD1 (0.35) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| Fluoride Ion SCHEMBL7640571 | 0.80 | ALDH1A1 (0.35) | CYP2A6ALDH1A1HPGDMAPK1HTR1A | |
| Fluoride Ion SCHEMBL7643351 | 0.80 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL5694274 | 0.79 | PDCD1 (0.37) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| Fluoride Ion SCHEMBL7636064 | 0.79 | PDCD1 (0.34) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| SCHEMBL4603520 | 0.78 | PDCD1 (0.36) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| SCHEMBL7030356 | 0.78 | PDCD1 (0.36) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| SCHEMBL28550963 | 0.78 | PDCD1 (0.36) | PDCD1CD274USP30CHRNB2CHRNA4 | |
| SCHEMBL7525652 | 0.78 | PDCD1 (0.36) | PDCD1CD274USP30CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143125-A1 | Catalyst component and catalyst system having a high polymerization activity for preparing polymers | KAMINSKY WALTER (DE) | 2002-10-03 | — | — | US | disclosed |
| US-6303718-B1 | PARTICULARLY A CATALYST SYSTEM CONSISTING OF METALLOCENE FLUORIDES AND ALUMINUM ALKYLS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-16 | — | — | US | disclosed |