SCHEMBL764410

SCHEMBL764410

C=C1Nc2ccccc2S1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 10/20 0.65
▸ MAPT P10636 8/20 0.65
▸ GAA P10253 7/20 0.65
▸ MEN1 O00255 4/20 0.65
▸ KMT2A Q03164 4/20 0.65
▸ SNCA P37840 3/20 0.65
▸ BCHE P06276 2/20 0.65
▸ ACHE P22303 2/20 0.65
▸ TDP1 Q9NUW8 2/20 0.65
▸ ALOX15 P16050 2/20 0.65
▸ ALOX12 P18054 2/20 0.65
▸ CYP1A2 P05177 1/20 0.65
▸ POLB P06746 1/20 0.65
▸ CYP3A4 P08684 1/20 0.65
▸ ADORA3 P0DMS8 1/20 0.65
▸ MAOA P21397 1/20 0.65
▸ CNR1 P21554 1/20 0.65
▸ PTGS1 P23219 1/20 0.65
▸ SLC6A2 P23975 1/20 0.65
▸ HTR2C P28335 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL29349533 0.79 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL9114 0.79 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.79 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 0.79 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29352248 0.79 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
SCHEMBL13873061 0.79 NOX1 (0.63) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL23683396 0.77 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22467844 0.77 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22467847 0.77 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL17028421 0.77 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116510-A 2-substituted methylene dihydrobenzo [ d ] thiazole derivatives and synthesis method and application thereof 华东师范大学 2020-05-08 — — CN claimed
EP-0379200-A2 Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-07-25 — — EP claimed
US-4785097-A Method for synthesizing spiro-oxazines PPG INDUSTRIES, INC. (US) 1988-11-15 — — US claimed
JP-62195076-A — — None — — JP disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 — — US disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11186669-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2021-11-30 — — US disclosed
US-20210284766-A1 RETARDATION FILM, ELLIPTICALLY POLARIZING PLATE, AND DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2021-09-16 — — US disclosed
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same DIC CORPORATION (JP) 2021-02-23 — — US disclosed
US-10723952-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-07-28 — — US disclosed
US-20070032493-A1 Method for treating B cell regulated autoimmune disorders SYNTA PHARMACEUTICALS CORP. (US) 2007-02-08 — — US disclosed
US-6936725-B2 Photochromic compounds RODENSTOCK GMBH (DE) 2005-08-30 — — US disclosed
CN-1139998-C Electrically erasable molecular base organic electric bistable film device and its producing technology 复旦大学 2004-02-25 — — CN disclosed
US-20030045714-A1 Photochromic compounds RODENSTOCK GMBH (DE) 2003-03-06 — — US disclosed
CN-1352470-A Electrically erasable molecular base organic electric bistable film device and its producing technology UNIV FUDAN (CN) 2002-06-05 — — CN disclosed
EP-0379200-A2 Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-07-25 — — EP disclosed
JP-S62195076-A NOVEL SPIRONAPHTHOPYRAN COMPOUND TORAY IND INC 1987-08-27 — — JP disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 — — US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030045714-A1 Photochromic compounds PPOX, NOP58, ROR1 NOX1 513/4885MAPT 1159/4885GAA 2883/4885
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same CRYAA, IK, LCP1 NOX1 4765/4885MAPT 161/4885GAA 2071/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH NOX1 2/4885MAPT 224/4885GAA 516/4885
US-10723952-B2 Polymerizable compound and optically anisotropic body SMC4, SMCHD1, PHOSPHO1 NOX1 4755/4885MAPT 17/4885GAA 2816/4885
US-20070032493-A1 Method for treating B cell regulated autoimmune disorders REL, NFATC1, BCL6 NOX1 628/4885MAPT 4316/4885GAA 3596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback