Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL814604 | 0.86 | LMNA (0.30) | — | |
| Hydrochloric Acid SCHEMBL6908236 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL78567 | 0.79 | POLB (0.33) | — | |
| Ethane SCHEMBL8633344 | 0.78 | — | — | |
| Bromide SCHEMBL7205887 | 0.76 | POLB (0.33) | — | |
| Fluoride Ion SCHEMBL1130886 | 0.76 | POLB (0.33) | — | |
| SCHEMBL4577361 | 0.76 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL731111 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL436801 | 0.74 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL31676791 | 0.74 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472490-B1 | AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6348556-B1 | COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6066709-A | Ethylene-aromatic vinyl compound copolymer and method for its production | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-23 | — | — | US | disclosed |
| US-5883213-A | STEREOREGULARITY | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5741868-A | Olefin polymerization process by using a substituted indenyl containing metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| US-5543373-A | OLEFIN POLYMERIZATION CATALYST | HOECHST AG (DE) | 1996-08-06 | — | — | US | disclosed |